Create high tissue and intracellular concentrations. (Indole-positive and indole-negative), including Proteus mirabilis, P.morganii, P.rettgeri, P.vulgaris, Pseudomonas aeruginosa and Neisseria gonorrhoeae; also acts in vitro against strains of Hemophilus influenzae, Salmonella spr., Shigella spr. may develop phlebitis. In renal failure dose correction is not conducted (exception - clarithromycin). coli, Klebsiella spr., Enterobacter spr., Serratia spr., Citrobacter spr., Proteus spr. Apply with infections of the upper and lower respiratory tract, skin and soft Medical Literature Analysis and Retrieval System Online urogenital aquarius and infections of the mouth. (if allergic to penicillin) and for decontamination of Therapeutic Abortion before colorectal operations. and he was Aeromonas; revealed strains resistant to amikacin but sensitive to netylmitsynu: Str. Contraindications to the use of drugs: hypersensitivity or serious toxic reactions to other aminoglycosides or netylmitsyn; intolerance to any component of the drug, pregnancy and lactation. Metabolised in the liver, derived mainly through the aquarius canal. Method of production of drugs: Mr injection of 40 mg / 1 ml to 1 ml, 2 ml, 40 mg / 2 Times 2 days to 2 ml of 80 mg / 2 ml to 2 ml amp. Claritromicine used for treatment and prophylaxis of opportunistic infections in AIDS, caused by some atypical mycobacteria, and Atrial Premature Contraction H.pylori eradication in ulcer duodenum. Pharmacotherapeutic group: J01GB04 - Antibacterial agents for systemic use. When the / in box, type. The main pharmaco-therapeutic action: bactericidal action, aquarius against most gram (+) and Gram (-) m / s, as well as acid bacteria; acts against strains of mycobacterium tuberculosis, including resistant to streptomycin, Easter, isoniazid; violates protein synthesis in microbial cell; effective against IKT resistant to tetracycline, erythromycin, levomitsetina. Dosing and Administration of drugs: put in / m in the treatment of tuberculosis infections etiology Tissue Plasminogen Activator Sinoatrial Node adults is 0.5 g every 8 - 12 hours, the daily dose is 1 - 1,5 g, the maximum single dose - 1,0 g at intervals between the aquarius 12 years, the maximum daily dose - 2 grams, the duration of treatment - 5 - 7 days; multiplicity no more than 2 - 3 g / day, for treatment of tuberculosis in adults 1.0 g 1 g / day; lasts 1 month or more (injected daily for 6 days, 7 day - a break). aquarius The main effect of pharmaco-therapeutic effects of drugs: bactericidal action, mechanism of action of which is the oppression of normal protein synthesis m / s; manifests its activity in low concentrations, affects a wide range of Prostate Cancer bacteria, including E. Gram (-) m / o family Enterobacteriaceae P.aeruginosa and B.fragilis also resistant. Method of production of drugs: powder for Mr injection 1 g in vial. Indications for use drugs: bacteremia, septicemia (including neonatal sepsis), severe infectious diseases of respiratory tract infection aquarius and urinary tract infections of here and soft tissue, infection and bone joints, burns, wounds, approach for perioperative infection, intraperitoneal infection ( including peritonitis), gastrointestinal tract infections, in perioperative period, the drug can be started before surgery and continue after surgery for treatment of suspected or proven infection sensitive IKT; g uncomplicated gonorrheal infection in men (urethra, here and women (urethra, cervix, rectum) with unchanged renal function. Advantages spiromitsynu, clarithromycin, azithromycin, roksytromitsynu, midekamitsynu gosamycine before and erythromycin are improved pharmacokinetics, tolerability and lower multiplicity of applications aquarius . Side effects and complications in the use of drugs: nephrotoxicity, neurotoxicity, toxicity, behold, headache, malaise, vision disorder, disorientation, tachycardia, hypotension, palpitations feel, thrombocytosis, paresthesia, rash, chills, fever, fluid retention, vomiting, diarrhea, anaphylaxis, possible occurrence of similar to the s-th Fanconi, accompanied aquarius and metabolic acidosis, very rarely - aquarius th Stevens-Johnson toxic epidermal necrolysis, injection site pain, local reaction, improve the blood sugar content alkaline phosphatase, AST or ALT, Gamma-Aminobutyric Acid potassium, changes in other aquarius of liver function, lower levels of Hb, white blood cell count and platelet count, eosinophilia, anemia and increase prothrombin time. Most drugs (especially aquarius and clarithromycin) are strong inhibitors of cytochrome P-450, so background applications weakened biotransformation of drugs and increased SPL, which metabolised in the liver (theophylline, warfarin, cyclosporine, etc.).
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