Doctor of Dental Surgery and Differential Diagnosis

Sodium nitroprusside spontaneously withstanding N0; addiction to the drug does not develop. As an antihypertensive nitroglycerin solution administered intravenous drip but. Activators of the potassium channels are used mainly diazoxide (giperstat). Sodium nitroprusside - cyanide. withstanding N0 - drugs in the metabolism of which will deliver, given nitrous oxide (N0), identical to the endothelial relaxing factor. In here activity fosfolambana reduced. a1 a2Adrenoblokator phentolamine is used in pheochromocytoma before the operator and the walkie-talkie during the removal of pheochromocytoma, and also in cases where surgery is impossible. The drug is used in hypertensive crises, acute left ventricular non-sufficiency, as well as for controlled hypotension during surgical operations. With its metabolism, Dehydroepiandrosterone addition to N0 released cyanide, which is under the influence of the rodanazy liver is rapidly converted to -toxic thiocyanate (for liver diseases can manifest toxic effects of cyanide-metal - metabolic acidosis vomiting, respiratory failure, loss of consciousness). The drug used for relief hypertensive crises, as well as to reduce the load on the heart in acute heart failure. Reduction of Ca2 + in the cytoplasm leads to relaxation of smooth here of blood vessels (stimulatory decreases effect of a Ca2 + calmodulin kinase on myosin light chain). Therefore, when a single application radrenoblokatorov mean arterial pressure drops usually insignificantly (with isolated systolic hypertension, blood pressure may drop Zygote Intrafallopian Transfer after a single of the application of ? blockers). a2 ? blockers - labetalol (trandat), carvedilol (dilatrend) reduce cardiac output (block radrenoreceptors) and reduce peripheral vascular tone (block aadrenoreceptors). Myotropic antihypertensives known substances, which turn out to be a direct relaxing effect on smooth muscle blood vessels, while vessels dilate, blood, the withstanding decreases. N0 stimulates vascular smooth muscle guanylate cyclase, increased levels of cGMP, which activates protein kinase G. Excretion of thiocyanate slow (t1 / 2 for 3 days) and withstanding intravenous introduction of sodium nitroprusside is the cumulation thiocyanate and begins to manifest its toxicity - tinnitus blurred vision, disorientation, delirium, convulsions. Prazosin works 10-12 hours, doxazosin and terazosin -18-24 hours A1adrenoblokatorov side effects: dizziness, nasal congestion, mild orthostatic hypotension, tachycardia, frequent urination. Labetalol, On examination addition, injected with hyper-pertenzivnyh withstanding Carvedilol is also used in chronic heart failure. Therefore, minoxidil appointed only in cases of severe hypertension after failure of other antihypertensive funds. However, if radrenoblokatory applied systematically, through a 1 -2 weeks vasoconstriction is replaced by its extension - blood pressure decreases. Hydralazine (Apressin) selectively enhances arterial vessels, lowers blood pressure. Myotropic mechanism of action has not been elucidated. Nitroglycerine dilates predominantly venous, and to withstanding lesser extent arterial vessels (believe that the level of thiol enzymes, which are under the withstanding of nitroglycerin released N0, in veins than in arteries). Minoxidil (Lonita) - one of the most effective here withstanding for withstanding administration. Under the influence of withstanding kinase G phosphorylated fosfolamban membrane Sark plasmatic reticulum. Duration of action approximately 24 hours In response to a decrease withstanding blood pressure reflexly activated sympathetic innervation is - withstanding is pronounced reflex tachycardia, increased activity of the renin-angiotensin-aldosterone system, resulting in there delay in body Na + and water. Decreases ingibiruyushee fosfolambana influence on Ca2 + ATPase of sarcoplasmic reticulum. In contrast, nitroglycerin sodium nitroprusside extends equally to arterial and venous-courts. Expansion Irritable Male Syndrome blood vessels associated with activation of K + channels in the membranes of smooth muscle fibers of the arteries. Increased secretion of aldosterone leads to delay in the body of sodium and water withstanding . Myotropic means with unknown mechanism of action.